Ph.D./Professor
Field:Stem Cell Biology; Muscle Regeneration; Epigenetics and Exercise
+862039310232
duanrui@m.scnu.edu.cn
- South China Normal University, Guangzhou, China B.S. 07/99 Biochemistry
- South China Normal University, Guangzhou, China M.S. 07/02 Physics
- Indiana University, Indianapolis, United States Ph.D. 06/08 Cellular Physiology
- Johns Hopkins University, Baltimore, United States Postdoc. 06/14 Molecular Biology and Genetics
- "Pearl River Scholar" Titled Professor, South China Normal University, Guangzhou, China 2018.10-Present
- Professor, Lab Head, Laboratory of Regenerative Medicine in Sports Science, South China Normal University, Guangzhou, China, 2017-Present
- Research Associate, Johns Hopkins University School of Medicine, Baltimore, United States, 2014-2016
- Lecturer, South China Normal University, Guangzhou, China, 2002-2003
Molecular and Cell Biology, Sports Physiology and Anatomy, Molecular Cloning Workshop
- "Spectrin and Cell Fusion", General Grant, National Natural Science Foundation of China (NSFC), 2018
- "Skeletal Muscle Regeneration and Aging", the Startup Fund, South China Normal University, China, 2017
- "Characterization of a novel regulator in myoblast fusion", Postdoctoral Fellowship, American Heart Association, 2012
Duan R, Kim JH, Shilagardi K, Schiffhauer E, Son S, Lee DH, Li S, Thomas G, Luo T, Fletcher DA, Robinson DN, Chen EH, Spectrin is a mechanoresponsive protein shaping fusogenic synapse architecture during myoblast fusion，Nature Cell Biology, 2018, 20(6):688-698.
Li FH, Li T, Ai JY, Sun L, Min Z, Duan R, Zhu L, Liu YY, Liu TC. Beneficial Autophagic Activities, Mitochondrial Function, and Metabolic Phenotype Adaptations Promoted by High-Intensity Interval Training in a Rat Model. Front Physiol. 2018, 9:571.
Wu C, Yang L, Tucker D, Dong Y, Zhu L, Duan R, Liu TC, Zhang Q. Beneficial Effects of Exercise Pretreatment in a Sporadic Alzheimer's Rat Model. Med Sci Sports Exerc. 2018, 50(5):945-956.
Kim JH, Jin P, Duan R, Chen EH. Mechanisms of myoblast fusion during muscle development. Curr Opin Genet Dev., 2015, 32:162-170.
Shilagardi K, Li S, Luo F, Marikar F, Duan R, Jin P, Kim JH, Murnen K, Chen EH. Actin-propelled invasive membrane protrusions promote fusogenic protein engagement during cell-cell fusion. Science, 2013, 340(6130):359-63.
Duan R, Jin P, Luo F, Anderson N and Chen EH. Group I PAKs Function Downstream of Rac to Regulate Podosome Invasion During Myoblast Fusion in vivo. J Cell Biol., 2012, 199(1):169-85.
Jin P*, Duan R*, Luo F, Zhang G, Hong N, Chen EH. Competition between Blown Fuse and WASP for WIP binding regulates the dynamics of WASP-dependent actin polymerization in vivo. Dev. Cell, 2011, 20(5):623-38. （*Co-First Author）
Sens K, Zhang S, Jin P, Duan R, Zhang G, Luo F, Parachini L and Chen EH. An Invasive Podosome-like Structure Promotes Fusion Pore formation during Myoblast Fusion. J Cell Biol. 2010, 191(5):1013-27.
Duan R and Gallagher PJ. Dependence of Skeletal Muscle Myoblast Fusion on a Novel Cortical Actin Wall and Nonmuscle Myosin IIA. Dev. Biol., 2009; 325(2):374-85.
Duan R, Zhu L, Liu TCY et al. Light emitting diode irradiation protect against the amyloid beta 25-35 induced apoptosis of PC12 cell in vitro. Lasers Surg. Med., 2003, 33:199–203.
Duan R, Liu TCY et al., Signal transduction pathway involved in low intensity He-Ne laser–induced respiratory burst in bovine neutrophils: a potential mechanism of low intensity laser biostimulation. Lasers Surg. Med., 2001, 29: 174-178.
Journal Reviewer
Ad-hoc Reviewer for Stem Cells, Methods, Biology of the Cell, Journal of Cellular Biochemistry, Cellular and Molecular Biology
Memberships
Sigma Xi, The Scientific Research Society; American Heart Association
Mentoring
2010-2016 Extracurricular Research for Undergraduate Students; Laboratory Skills for Graduate Students, Johns Hopkins University School of Medicine, Baltimore, US
2017-Present Graduate Students, South China Normal University, Guangzhou, China
Postdoctoral Fellow: Wenzhen Ding
Ph.D. Students: Guan Yang, Fan Li
M.S. Students: Yuecheng Li, Ni Luo, Haiwang Shi, Limin Yu, Yuexiang Huang, Zhiyue Wang
Talent Award, Guangdong Physiologist Association, China, 2018; American Heart Association Postdoctoral Fellowship, 2012; Langman Award and Students Travel Fellow, 2007
Educational Enhancement Travel Grant, Indiana University, 2007; Sigma Xi Student Research Award, Indiana University Chapter, 2006; University Fellowship, Indiana University, 2004; Travel Grant of the 23rd Annual Meeting of American Society for Laser in Medicine and Surgery, Inc. ASLMS, 2003; University Fellowship, South China Normal University, China, 2001; Student/Resident Research Award for its excellence in the specialty of Biostimulation & Summer Research Grant, American Society for Laser in Medicine and Surgery, Inc. ASLMS, 2000; Honorary Undergraduate Student, Guangdong Province, China, 1999
